Exploring left ventricle dimensions and interventricular septum thickness in the Iranian population: A comparative
Naser Khezerlouy-Aghdam1, Shahla Meshgi1, Zahra Hosnavi1
1Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Insights
Electrocardiogram (ECG)-gated computed tomography angiography (CTA) and echocardiography show significant correlations for assessing left ventricular (LV) dimensions and interventricular septum (IVS) thickness in the Iranian population. Both methods are valuable for diagnosing cardiovascular diseases (CVDs).
Area of Science:
- Cardiology
- Medical Imaging
- Diagnostic Techniques
Background:
- Cardiovascular diseases (CVDs) are a major global health concern, with significant impact in Iran.
- Accurate assessment of left ventricular (LV) dimensions and interventricular septum (IVS) thickness is vital for diagnosing and managing cardiac conditions.
- Comparing imaging modalities for these measurements is crucial for clinical practice.
Purpose of the Study:
- To compare left ventricular (LV) dimensions and interventricular septum (IVS) thickness measurements obtained via electrocardiogram (ECG)-gated computed tomography angiography (CTA) and echocardiography.
- To evaluate the correlation between these two imaging techniques in an Iranian population.
Main Methods:
- A cross-sectional study involving 160 Iranian individuals without known CVD.
- Participants underwent both ECG-gated CTA and echocardiography for LV and IVS measurements.
- Statistical analysis using Pearson's correlation coefficient to assess agreement between modalities.
Main Results:
- Significant correlations (p<0.000) were observed between LV dimensions and IVS thickness measurements from both echocardiography and CTA.
- Strong correlations were found across various cardiac views and regions, including parasternal long-axis (PLAX), Mid, Base views, and anteroseptal/inferoseptal regions.
- Echocardiography measurements also demonstrated significant correlations, with varying strengths.
Conclusions:
- ECG-gated CTA and echocardiography show significant correlation in assessing LV dimensions and IVS thickness.
- Both imaging techniques hold potential clinical utility for diagnosing and managing CVD in the Iranian population.
- The 4-chamber and PSAX methods may be used interchangeably for IVS thickness measurement; further validation is recommended.
Background:
Cardiovascular diseases (CVDs) are a significant cause of morbidity and mortality worldwide, particularly among the Iranian population. Assessing left ventricular (LV) dimensions and interventricular septum (IVS) thickness is crucial in diagnosing and managing various cardiac conditions. This study aimed to compare LV dimensions and IVS thickness using electrocardiogram (ECG) gated computed tomography angiography (CTA) and echocardiography.
Methods:
A cross-sectional study was conducted on 160 Iranian individuals without known CVD from March to September 2023 in Hospital, Tabriz, Iran. Participants underwent both ECG-gated CTA and echocardiography for assessment of LV dimensions and IVS thickness. Measurements were performed by experienced radiologists and cardiologists, respectively. Echocardiography and CTA were analyzed for their correlation using Pearson's correlation coefficient. Statistical analysis was conducted using SPSS V25 software.
Results:
The study revealed a significant correlation between various LV dimensions and wall thickness measurements obtained from echocardiography and CTA (p<0.000). Strong and significant correlations were found in measurements taken from different views and regions of the heart, including the parasternal long-axis (PLAX) view, Mid and Base views, and the anteroseptal and inferoseptal regions (p<0.000). Echocardiography measurements also showed significant correlations, with varying strengths.
Conclusion:
The comparative analysis of LV dimensions and IVS thickness using ECG-gated CTA and echocardiography demonstrated significant correlations, suggesting the potential clinical utility of both imaging techniques in diagnosing and managing CVD in the Iranian population. The 4-chamber and PSAX methods can be used interchangeably to measure interventricular septum thickness. Further research is required to validate and expand upon these results.
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