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[Long COVID: therapeutic challenges and opportunities in the face of persistent sequelae]
Salma Bessalah1, Divya Sinha1, Xinchen Yuan1
1CIRI - Centre international de recherche en infectiologie, Equipe GIMAP ; Université Claude Bernard Lyon 1 ; Inserm U1111 ; CNRS UMR5308, ENS-Lyon ; CIC 1408 vaccinologie, Saint-Étienne, France.
Abstract:
The COVID-19 pandemic, caused by SARS-CoV-2, has not only led to a global health and economic crisis but also renewed attention to a clinical phenomenon of persistent symptoms after viral infection. This phenomenon is defined as long COVID or post-COVID-19 syndrome. Approximately one in eight patients experience persistent symptoms of varying intensity after the acute phase of the infection. This phenomenon, combined with the virus's high transmissibility and rapid mutation rate, poses a major public health challenge. This review examines various therapeutic approaches currently under consideration for treating long COVID, and explores future prospects in this field.
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