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Design a model to predict incomplete immunization among Ethiopian children using ensemble machine learning
Birku Getie Mihret1,2, Betelhem Nega Belay3, Jenberu Mekurianew Kelkay4
1Department of Computer Science, College of Computational Sciences, Debark University, Debark, Ethiopia. birkugetie2010@gmail.com.
Scientific Reports
|December 12, 2025
Summary
This study used ensemble machine learning to identify factors behind incomplete childhood immunization in Ethiopia. Key factors identified include marital status and residence, enabling targeted public health interventions.
Area of Science:
- Public Health
- Computational Biology
- Machine Learning
Background:
- Immunization is a crucial, cost-effective public health strategy globally.
- Ethiopia faces challenges in achieving optimal childhood immunization coverage.
- Understanding factors influencing incomplete immunization is vital for improving child health outcomes.
Purpose of the Study:
- To identify key determinants of incomplete immunization among children aged 0-59 months in Ethiopia.
- To leverage ensemble machine learning techniques for accurate prediction and analysis.
- To inform targeted public health interventions for enhanced immunization coverage.
Main Methods:
- Utilized 16,394 Ethiopian Demographic and Health Survey (EDHS) datasets, split into 80% training and 20% testing sets.
- Employed various ensemble machine learning algorithms including Bagging (Random Forest), Boosting (XGBoost, LightGBM, CatBoost), and Voting ensembles.
- Implemented Stacking models with XGBoost/CatBoost as base learners and other ML algorithms as meta-models, all in Python.
Main Results:
- The bagging meta-estimator + XGBoost voting model achieved the highest performance: 95.94% accuracy, 95.89% F1-score, 94.81% recall, and 97.07% precision.
- The model demonstrated high reliability with a 96% AUC-ROC value and 95.75% cross-validation score.
- Marital status and place of residence were identified as the most significant factors associated with incomplete immunization.
Conclusions:
- Ensemble machine learning effectively identifies critical factors influencing childhood immunization status in Ethiopia.
- Marital status and residence are key demographic factors requiring attention in immunization programs.
- The study's findings offer valuable insights for developing targeted interventions to improve immunization coverage and child health.
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