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Technology for Detecting Keratinocyte Carcinoma From Mohs Micrographic Surgery Fresh Frozen Sections: A Systematic
Cathy Zhao1,2, Simon Lee1
1The Skin Hospital, Darlinghurst, New South Wales, Australia.
The Australasian Journal of Dermatology
|December 13, 2025
Abstract:
We reviewed the role of technologies, including artificial intelligence (AI), confocal microscopy (CM), optical coherence tomography (OCT), and Raman micro-spectroscopy (RMS) to assist in detecting keratinocyte carcinoma (KC) from Mohs micrographic surgery (MMS) fresh frozen sections (FFS). AI is potentially capable of screening MMS FFS while also improving the accuracy of the imaging modalities. Further developments and validation studies are required.
