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Ramadan fasting in multiple sclerosis: A systematic review.
Ahad Nourmohammad1, Meysam Zorriyeh-Sheikhali2, Sarvin Sanaie3
1Research Center for Evidence-Based Medicine, Iranian EBM Centre: A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran.
Multiple Sclerosis and Related Disorders
|December 13, 2025
Summary
Ramadan fasting may improve quality of life for multiple sclerosis (MS) patients with mild disability. However, higher disability and longer disease duration increase MS activation risk during Ramadan observance.
Area of Science:
- Neurology
- Clinical Medicine
- Public Health
Background:
- Ramadan observance involves daily fasting from sunrise to sunset.
- The impact of Ramadan fasting on multiple sclerosis (MS) patients is a significant clinical concern.
- Understanding these effects is crucial for patient management during Ramadan.
Conclusions:
- Limited evidence suggests Ramadan fasting may enhance quality of life in MS patients with mild disability.
- No significant adverse effects were observed, but findings require cautious interpretation due to small study sizes.
- Higher disability levels and longer disease duration are risk factors for MS exacerbation during Ramadan.
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