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Diffuse Low-Grade Glioma With Spontaneous Radiological Regression: A Case to Be Followed
Abdelkouddouss Laaidi1, Oufaa Jamal2, Abd El Hamid Jehri2
1Neurosurgery, University Hospital of Casablanca, Casablanca, MAR.
Cureus
|December 15, 2025
Summary
Spontaneous regression of low-grade glioma (LGG) is extremely rare. This case documents significant tumor shrinkage and neurological improvement in a young woman with diffuse LGG, suggesting potential new therapeutic avenues.
Area of Science:
- Neuro-oncology
- Brain Tumor Research
- Rare Medical Phenomena
Background:
- Low-grade gliomas (LGGs) are slow-growing brain tumors with a propensity for progression.
- Spontaneous regression of LGG is exceptionally rare, with limited understanding of its underlying mechanisms.
