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Preregistration of high-quality protocols in pharmacoepidemiology research
Henrik Larsson1, Zhang Chang2, Kenneth K C Man3
1School of Medical Sciences Örebro University Örebro Sweden.
None:
Pharmacoepidemiology studies are an important complement to Randomized Clinical trials, but such studies face several challenges, such as confounding and selective reporting. How to best address confounding has been discussed in detail for many years. More recent discussions have highlighted the value of pharmacoepidemiology studies based on pre-registered protocols. This is an important step to address problems related to selective reporting and to enhance transparency and reproducibility. In this editorial perspective, we discuss the value of pre-registered protocols in pharmacoepidemiology.
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