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Published on: May 2, 2018
Patient Factors Contributing to Wireless pH Monitoring Intolerance
Maria Krakovski1, Katelyn Madigan2, Alexa Cecil2
1Department of Medicine, Emory University School of Medicine, Atlanta, GA.
Wireless pH capsule endoscopy intolerance is linked to irritable bowel syndrome (IBS), depression, and capsule retention. Antidepressant use may reduce postprocedure pain, warranting further study.
Area of Science:
- Gastroenterology
- Medical Devices
- Patient Outcomes
Background:
- Wireless capsule endoscopy is vital for measuring esophageal acid exposure.
- While generally safe, complications like capsule retention and pain can occur.
- Patient intolerance post-procedure is a significant concern.
Purpose of the Study:
- To identify factors contributing to intolerance after wireless pH capsule endoscopy.
- To analyze the relationship between patient characteristics and postprocedure pain.
Main Methods:
- Retrospective analysis of 204 patients undergoing wireless pH monitoring (Jan 2017-June 2023).
- Descriptive statistics and statistical tests of association were employed.
- Multivariate logistic regression modeled postprocedure pain predictors.
Main Results:
- 8.73% of patients reported severe postprocedural pain.
- Irritable bowel syndrome (IBS) and capsule retention were significantly associated with pain.
- Depression increased pain odds (OR 8.18), while antidepressant use decreased them (OR 0.17).
Conclusions:
- Postprocedural intolerance is associated with IBS, depression, and capsule retention.
- Antidepressant use appears protective against postprocedure pain.
- Further research is needed to confirm the protective role of antidepressants.
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