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Association of Cannabis and Cigarette Use With Eustachian Tube Dysfunction
Kaitlin Hori1, Alexander Cobian1, Tyler Gallagher2
1Keck School of Medicine, University of Southern California, Los Angeles, CA.
Regular cannabis use and combined use of cannabis, e-cigarettes, and cigarettes are linked to obstructive eustachian tube dysfunction (OETD). This study highlights potential risks of substance use on middle ear pressure.
Area of Science:
- Otolaryngology
- Public Health
- Substance Use Research
Background:
- Obstructive eustachian tube dysfunction (OETD) affects middle ear pressure.
- Understanding risk factors for OETD is crucial for public health.
- Cannabis, e-cigarette, and cigarette use are prevalent among US adults.
Purpose of the Study:
- To investigate the association between cannabis use and obstructive eustachian tube dysfunction (OETD).
- To examine the combined effects of cannabis, e-cigarettes, and cigarettes on OETD.
- To analyze these associations in a representative sample of US adults.
Main Methods:
- Cross-sectional analysis of National Health and Nutrition Examination Survey data (2015-2018).
- Participants (n=2777) with tympanometry and substance use data were included.
- Multivariable logistic regression models adjusted for confounding factors.
Main Results:
- Regular cannabis use was significantly associated with OETD (OR: 1.95).
- Both ever and regular cigarette use were linked to OETD (ORs: 1.62, 2.18).
- Combined use of all three substances showed a significant association with OETD (OR: 2.10).
- E-cigarette use alone was not independently associated with OETD.
Conclusions:
- Regular cannabis use is associated with increased odds of OETD.
- Combined use of cannabis, e-cigarettes, and cigarettes may elevate OETD risk.
- Further research is warranted to elucidate the independent and combined effects of these substances on eustachian tube function.
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