Related Experiment Video
Updated: Jan 8, 2026

Neutrophil Isolation and Analysis to Determine their Role in Lymphoma Cell Sensitivity to Therapeutic Agents
Published on: March 25, 2016
Neutrophil Cannibalism by Tumor Cells in Squamous Cell Carcinoma: Cytologic Features and Clinical Implications
Sophia Zhang1, Jan F Silverman1
1Department of Pathology and Laboratory Medicine, University of North Carolina Medical Center, Chapel Hill, North Carolina, USA.
Abstract:
Neutrophil cannibalism or engulfment by tumor cells is a feature often associated with aggressive malignancies. Although metastatic squamous cell carcinoma is commonly diagnosed by fine needle aspiration cytology, there are only rare reports of neutrophil cannibalism by squamous cell carcinoma in current cytology literature. We present two cases of metastatic squamous cell carcinoma featuring prominent neutrophil cannibalism diagnosed by fine needle aspiration cytology, describe their unique cytologic features, and discuss the prognostic implications of this diagnosis.
More Related Videos
08:59Neutrophil Extracellular Traps Generated by Low Density Neutrophils Obtained from Peritoneal Lavage Fluid Mediate Tumor Cell Growth and Attachment
Published on: August 3, 2018
07:29Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
Related Concept Videos
Adaptive Mechanisms in Cancer Cells
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
The Tumor Microenvironment
Cancer