Related Experiment Video
Updated: Jul 26, 2026
Pre-clinical Orthotopic Murine Model of Human Prostate Cancer
Published on: August 29, 2016
Ectopic Prostate Tissue in the Bladder Exhibiting Fluorescence on Photodynamic Diagnosis: A Report of Two Cases
Michinori Shimizu1,2, Jun Kamei1, Daisuke Yamada1,3
1Department of Urology The University of Tokyo Graduate School of Medicine Tokyo Japan.
Introduction:
We report two cases of ectopic prostate tissue exhibiting fluorescence during photodynamic diagnosis using 5-aminolevulinic acid.
Case Presentation:
The first case involved a 57-year-old man with a 9-mm papillary tumor on the right side of the bladder neck. The second case involved a 75-year-old man with a history of left renal pelvic cancer who presented with a 2-mm papillary tumor in the bladder trigone. In both cases, the tumors fluoresced red under blue light during photodynamic diagnosis-assisted transurethral resection. Histopathological examination revealed ectopic prostate tissue in both cases. No recurrence was observed, and a slight decrease in serum prostate-specific antigen levels was noted at 12 and 5 months of follow-up in cases 1 and 2, respectively.
Conclusion:
Ectopic prostate tissue in the bladder is a rare benign tumor that may exhibit false-positive fluorescence during photodynamic diagnosis, making it difficult to distinguish from bladder cancer even with this technique.
