Related Experiment Video

Updated: Jan 8, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
04:04

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

352

Recurrent Nasopharyngeal Chordoma Stabilized With Afatinib: A Case Report

Christopher C Chen1, Vincent Yeung2

  • 1Internal Medicine, Rutgers New Jersey Medical School, Newark, USA.

Cureus
|December 17, 2025
PubMed
Summary

This case study highlights a rare extraosseous chordoma near the skull base. Afatinib, an EGFR inhibitor, showed potential as a targeted therapy for this challenging diagnosis.

Keywords:
afatinibbrachyurychordomaepidermal growth factor receptor (egfr)tyrosine kinase inhibitor (tki)

More Related Videos

Surgical Treatment of an Endolymphatic Sac Tumor04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

1.4K
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

4.1K

Related Concept Videos

Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.7K
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
738