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Intellectual Disability01:29

Intellectual Disability

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Intellectual disability (ID) is a neurodevelopmental condition characterized by deficits in intellectual and adaptive functioning that manifest during the developmental period. This condition encompasses challenges in reasoning, memory, problem-solving, and learning, accompanied by impairments in everyday life skills, such as communication, self-care, and social interactions. Intellectual disability affects approximately 1% of the population in the United States, impacting an estimated 5...
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During adolescence, individuals experience significant cognitive development that enhances their understanding of others' emotions and thoughts, known as cognitive empathy. This period is marked by an increased ability to adapt to others' perspectives and a more nuanced understanding of others' mental states, a skill that is foundational for social problem-solving and conflict avoidance. The development of cognitive empathy relies heavily on the theory of mind — the...
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Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
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Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
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Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
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Social-emotional experiences and cultural influences play significant roles in shaping gender development. During middle childhood, from ages 6 to 11, peer groups become dominant in reinforcing gender norms. Children in this age group often align with same-gender peer groups, which actively encourage behaviors that conform to traditional gender roles. For instance, boys may be discouraged from engaging in activities perceived as feminine, reinforcing culturally dictated norms about masculinity...
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Related Experiment Video

Updated: Jan 8, 2026

Multimodal Protocol for Assessing Metacognition and Self-Regulation in Adults with Learning Difficulties
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Gender transition and intellectual developmental disorders: a case report.

Lorenzo Soldati1,2, Fabienne Gerber3, Sotiria Maria Iliopoulou3

  • 1Sexual Medicine and Sexology Unit, Division of Psychiatric Specialties, Department of Psychiatry, University Hospital of Geneva, Geneva, Switzerland.

Sexual Medicine
|December 17, 2025
PubMed
Summary

This case study details a transgender man with intellectual developmental disorder (IDD) and bipolar disorder who successfully underwent gender-affirming treatments. The interventions led to a significant reduction in gender incongruence and psychiatric symptoms, improving his social functioning.

Area of Science:

  • Endocrinology
  • Psychiatry
  • Genetics

Background:

  • Gender incongruence (GI) is frequently associated with mental health conditions.
Keywords:
autonomygender incongruence (GI)gender-affirming surgery (GAS)intellectual developmental disorders (IDDs)mental disordersself-determination

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  • Limited research exists on gender incongruence in individuals with intellectual developmental disorder (IDD).
  • No prior data available on gender-affirming treatments for individuals with both GI and IDD.