New Applications of Intense Pulsed Light in Facial Rejuvenation

Intense pulsed light (IPL) is a noninvasive technology that targets chromophores in the skin through selective photothermolysis. IPL system with a 755-nm filter penetrates the reticular dermis to generate photothermal effects. However, the clinical efficacy and collagen remodeling mechanisms remain underexplored.

This study evaluates the efficacy and safety of the IPL system with a 755-nm filter in improving skin photoaging and laxity among Asian patients with Fitzpatrick skin types II-IV.

A cohort of 61 patients with Fitzpatrick skin types II-IV (55 females, 6 males; mean age 36.05 ± 6.84 years) were included. Treatments were administered in 3 phases. Efficacy and safety were assessed through medical photography, VISIA skin analyzer, infrared thermography, and VAS pain scores.

Immediate facial tightening and jawline contouring were observed post-treatment. Infrared thermography revealed a dose-dependent temperature increase correlated with treatment parameters. 63.93% (39/61) of patients reported VAS pain scores ≤1, while transient erythema (n = 6) and acneiform eruptions (n = 3) were noted as minor adverse events. No severe complications occurred.

The IPL-755 nm system offers a safe and effective approach for facial rejuvenation. Nevertheless, the long-term mechanisms of collagen regeneration require further investigation.