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Genetic diversity, population structure and selective sweeps in Italian Leccese chickens
Medhat S Saleh1, Giusy Rusco2, Filippo Cendron3
1Department of Veterinary Medicine, University of Bari Aldo Moro, Valenzano, 70010 BA, Italy; Department of Animal Production, Faculty of Agriculture, Benha University, 13736 Benha, Egypt.
Genetic characterization of the Leccese (LEC) chicken breed reveals unique diversity and population structure. This study identifies key genes for growth, disease resistance, and adaptation, crucial for conservation and breeding programs.
Area of Science:
- Animal Genetics
- Poultry Science
- Conservation Genetics
Background:
- Italy possesses diverse native chicken breeds, including the Leccese (LEC) breed.
- Urgent genetic characterization of the LEC breed is needed for conservation and sustainable development.
Purpose of the Study:
- To genetically characterize the Leccese chicken breed.
- To assess its genetic diversity and population structure.
- To identify selection signatures for conservation and breeding.
Main Methods:
- Utilized the 600K Affymetrix SNP array for genetic analysis.
- Compared LEC with 25 Italian indigenous breeds and four commercial lines.
- Employed runs of homozygosity and integrated haplotype score analyses for selection signatures.
Main Results:
- LEC chicken exhibits distinct genetic diversity (heterozygosity 0.343-0.358) and population structure.
- Identified significant inbreeding coefficients (0.044-0.189).
- Detected selection signatures in genes related to growth, bone development, disease resistance, and adaptation.
Conclusions:
- Provides novel insights into the LEC chicken's genetic background, aiding breed identification and conservation.
- Identified candidate genes can inform future breeding programs for enhanced traits and adaptation.
- Supports sustainable development and conservation planning for the Leccese chicken breed.
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