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Gaining extensive resistance against clubroot disease through the disruption of a susceptibility gene
Qibin Wu1, Zhen Zeng1, Daowen Wang2
1State Key Laboratory of Tropical Crop Breeding, Institute of Tropical Bioscience and Biotechnology, Sanya Research Institute, Chinese Academy of Tropical Agricultural Sciences, Sanya, 572024, China.
Journal of Integrative Plant Biology
|December 17, 2025
Abstract:
This Commentary examines research by Wu et al. showing that β-1,3-glucan synthase-like 5 (GSL5) functions as a key gene for susceptibility to clubroot in Brassica family members by suppressing immunity regulated by jasmonic acid. Inaction of GSL5 through genome editing provides broad-spectrum resistance to clubroot.
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