Related Experiment Video
Updated: Jan 8, 2026

Measuring Local Anaphylaxis in Mice
Published on: October 14, 2014
[Updated guidelines for anaphylaxis management - simplified structures for enhanced patient safety]
1docent, överläkare, ME lung- och allergisjukdomar, Karolinska universitetssjukhuset, Stockholm; ordförande, SFFA:s arbetsgrupp för anafylaxi.
Abstract:
The updated Swedish guidelines for anaphylaxis, published by the Swedish Association for Allergology (SFFA) in the autumn of 2024, provide evidence-based recommendations for acute care. The guidelines highlight the importance of rapid intervention and clear diagnostic standards to ensure patient safety. Immediate intramuscular administration of adrenaline is the only evidence-based intervention in the acute phase and should occur without delay or consideration of severity grading. Routine use of corticosteroids is no longer recommended, and severity grading is replaced by NIAID/FAAN criteria. Antihistamines are reserved for post-stabilization. Documentation, observation, and control of serum tryptase levels are essential for continued care, diagnostic accuracy, and long-term management.
Related Concept Videos
Allergic Reactions
Asthma-IV: Nursing Management
First, in...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Cardiopulmonary Resuscitation IV: Pharmacological Management
Adrenergic Agonists: Therapeutic Uses
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

