Body Mass Index and Its Influence on Electrocardiographic Parameters in Healthy and Cardiovascular Patients

Roholla Hemmati1, Mohanna Parvenous2, Dorsa Bahrami Zanjanbar3,4

  • 1Department of Cardiology School of Medicine Ilam University of Medical Sciences Ilam Iran.

Obesity Science & Practice
|December 18, 2025
PubMed

Insights

Body mass index (BMI) influences electrocardiographic (ECG) parameters, impacting cardiovascular risk. Maintaining a healthy BMI is crucial for reducing the risk of cardiovascular diseases (CVDs) and promoting heart health.

Area of Science:

  • Cardiology
  • Public Health
  • Biomedical Engineering

Background:

  • Cardiovascular diseases (CVDs) are a leading global cause of mortality.
  • Key lifestyle factors contributing to CVDs include smoking, poor diet, inactivity, and stress.
  • Body Mass Index (BMI) is a critical indicator of body fatness and a potential risk factor for CVDs.

Purpose of the Study:

  • To investigate the relationship between electrocardiographic (ECG) changes and various BMI categories.
  • To analyze how demographic factors like age, gender, height, and weight influence this relationship.
  • To understand the implications of BMI on cardiac electrical activity.

Main Methods:

  • A cross-sectional study involving 964 patients from Mostafa Khomeini Hospital, Iran.
  • Utilized a 12-lead electrocardiogram (ECG) to record cardiac electrical activity.
  • Employed Pearson correlation coefficients and regression models (SPSS v. 24) to analyze data.

Main Results:

  • A 10-cm increase in height correlated with a 0.089 ms decrease in PR interval.
  • A 5-kg weight gain was associated with a 0.20 ms increase in PR interval and a 0.03 ms increase in QRS interval.
  • QT interval decreased by 1.34 ms with a 5-kg weight gain, while height changes showed no significant effect.

Conclusions:

  • ECG parameters are significantly influenced by BMI, suggesting a link to cardiovascular risk.
  • Elevated PR and QRS intervals, reduced QRS voltage, and altered ST segments/QT intervals indicate potential risks.
  • Maintaining a healthy BMI is essential for mitigating CVD risk and improving overall heart health.
Abstract

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