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Published on: February 19, 2022
Gastroschisis: diagnosis, prognosis and treatment options
Dastan Rustemov1, Zhenis Sakuov1, Zhuldyz Kucherbayeva1
1Department of Pediatric Surgery, University Medical Center, Mother and Child Center, Astana, Kazakhstan.
Insights
Gastroschisis, a congenital defect, causes abdominal organs to protrude through an abdominal wall opening. This review covers recent data on causes, diagnosis, treatment, and complications of gastroschisis.
Area of Science:
- Neonatal surgery
- Pediatric surgery
- Congenital anomalies
Background:
- Gastroschisis is a congenital anomaly with organs extruding through an abdominal wall defect.
- It is associated with significant morbidity and mortality despite medical advances.
Purpose of the Study:
- To review recent epidemiological data, etiological hypotheses, and diagnostic and treatment strategies for gastroschisis.
- To discuss postoperative complications and challenges in optimizing outcomes for gastroschisis patients.
Main Methods:
- Literature review of recent epidemiological data.
- Analysis of etiological hypotheses.
- Evaluation of current diagnostic and treatment strategies, including surgical tactics.
Main Results:
- Gastroschisis presents in simple and complicated forms, influenced by viscero-abdominal disproportion and anomalies.
- Recent surgical modifications like staged reduction and siloplasty are being evaluated.
- Ongoing challenges include optimizing surgical timing and minimizing complications.
Conclusions:
- Effective management of gastroschisis requires addressing viscero-abdominal disproportion and associated anomalies.
- Innovations in surgical techniques aim to improve outcomes for neonates with gastroschisis.
- Further research is needed to optimize surgical timing and reduce long-term complications.
Abstract:
Gastroschisis is a rare congenital anomaly characterized by extrusion of abdominal organs through a defect in the anterior abdominal wall, typically to the right of the umbilical cord. Despite advances in prenatal diagnostics and neonatal surgical care, gastroschisis remains associated with significant morbidity and mortality. This review summarizes recent epidemiological data, etiological hypotheses, diagnostic approaches, treatment strategies, and postoperative complications. Both simple and complicated forms are discussed, with emphasis on the impact of viscero-abdominal disproportion and associated anomalies. Recent modifications in surgical tactics, including staged reduction and innovative siloplasty techniques, are evaluated. The review highlights ongoing challenges in optimizing surgical timing, minimizing complications such as adhesive disease and necrotizing enterocolitis, and improving long-term outcomes.
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