Gastroschisis: diagnosis, prognosis and treatment options

Dastan Rustemov1, Zhenis Sakuov1, Zhuldyz Kucherbayeva1

  • 1Department of Pediatric Surgery, University Medical Center, Mother and Child Center, Astana, Kazakhstan.

Frontiers in Pediatrics
|December 18, 2025
PubMed

Insights

Gastroschisis, a congenital defect, causes abdominal organs to protrude through an abdominal wall opening. This review covers recent data on causes, diagnosis, treatment, and complications of gastroschisis.

Area of Science:

  • Neonatal surgery
  • Pediatric surgery
  • Congenital anomalies

Background:

  • Gastroschisis is a congenital anomaly with organs extruding through an abdominal wall defect.
  • It is associated with significant morbidity and mortality despite medical advances.

Purpose of the Study:

  • To review recent epidemiological data, etiological hypotheses, and diagnostic and treatment strategies for gastroschisis.
  • To discuss postoperative complications and challenges in optimizing outcomes for gastroschisis patients.

Main Methods:

  • Literature review of recent epidemiological data.
  • Analysis of etiological hypotheses.
  • Evaluation of current diagnostic and treatment strategies, including surgical tactics.

Main Results:

  • Gastroschisis presents in simple and complicated forms, influenced by viscero-abdominal disproportion and anomalies.
  • Recent surgical modifications like staged reduction and siloplasty are being evaluated.
  • Ongoing challenges include optimizing surgical timing and minimizing complications.

Conclusions:

  • Effective management of gastroschisis requires addressing viscero-abdominal disproportion and associated anomalies.
  • Innovations in surgical techniques aim to improve outcomes for neonates with gastroschisis.
  • Further research is needed to optimize surgical timing and reduce long-term complications.

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