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Updated: Jan 8, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
[Soft tissue sarcomas : essential multidisciplinary management]
Matthieu Zingg1, Sana Boudabbous2, Essia Saiji3
1Service de chirurgie orthopédique et traumatologie de l'appareil moteur, Hôpitaux universitaires de Genève, 1211 Genève 14.
None:
Soft tissue sarcomas are rare malignant tumors of mesenchymal origin, accounting for approximately 1 % of adult cancers. Their diagnostic and therapeutic complexity requires multidisciplinary management at specialized reference centers. Diagnosis relies on imaging, primarily MRI, as well as on anatomopathological and molecular analysis of a planned biopsy. Surgery with negative margins (R0) remains the standard treatment, often combined with neoadjuvant radiotherapy or chemotherapy, depending on the lesion's type, grade, and resectability. Systematic discussion within a multidisciplinary sarcoma tumor board optimizes the therapeutic strategy, reduces diagnostic errors, and improves both overall and functional patient outcomes.

