Related Experiment Video

Updated: Jan 7, 2026

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery
06:26

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery

Published on: May 16, 2021

5.4K

Accelerating the discovery of MET inhibitors powered by high-throughput hit identification

Hua Zhang1, Liwen Zhang2, Chang Liu3

  • 1Department of Medical Oncology, Jilin City Central Hospital, Jilin City, Jilin, China.

Bioanalysis
|December 18, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Mesenchymal-epithelial transition factor (MET)high-throughput screeninghit identificationinhibitor discoverymass spectrometry

More Related Videos

Identification of Kinase-substrate Pairs Using High Throughput Screening
11:13

Identification of Kinase-substrate Pairs Using High Throughput Screening

Published on: August 29, 2015

8.5K
A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules
08:43

A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules

Published on: March 10, 2017

10.8K

Related Experiment Videos

Last Updated: Jan 7, 2026

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery
06:26

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery

Published on: May 16, 2021

5.4K
Identification of Kinase-substrate Pairs Using High Throughput Screening
11:13

Identification of Kinase-substrate Pairs Using High Throughput Screening

Published on: August 29, 2015

8.5K
A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules
08:43

A Fluorescence-based Lymphocyte Assay Suitable for High-throughput Screening of Small Molecules

Published on: March 10, 2017

10.8K

Related Concept Videos

Drug Discovery: Overview01:26

Drug Discovery: Overview

10.9K
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
10.9K

Articles linked to this work by shared authors, journal, and citation graph.

An Ultra-High Throughput Hydrogen-Deuterium Exchange Workflow Using Acoustic Ejection Mass Spectrometry for Studying Peptide Solution Structural Conformation.

Analytical chemistry·2026

Rapid Screening and Prioritization of Culture Conditions for Natural Product Discovery using the Liquid Microjunction Surface Sampling Probe.

Journal of the American Society for Mass Spectrometry·2025

Ultra-high throughput mass spectrometry with ultra high-speed separations: differential mobility spectrometry-acoustic ejection mass spectrometry (DAEMS).

Bioanalysis·2025

High-Throughput Detection and Quantitation of Metal Contamination with Acoustic Ejection Mass Spectrometry.

Journal of the American Society for Mass Spectrometry·2025

Acoustic ejection mass spectrometry: the potential for personalized medicine.

Expert review of proteomics·2025

A Differential Ion Mobility Acoustic Ejection Mass Spectrometer System for Screening Isomerization-Mediating Enzyme Drug Targets.

bioRxiv : the preprint server for biology·2025

From anti-drug antibody incidence to clinical relevance: interpreting highly sensitive immunogenicity assays in biosimilars.

Bioanalysis·2026

Vaccine Ligand Binding Assay Development.

Bioanalysis·2026

From analytical similarity to clinical confidence: how regulatory evolution ensures comparable immunogenicity in streamlined biosimilar development.

Bioanalysis·2026

A DAR sensitive hybrid LBA-LC-MS/MS assay for quantitation of conjugated payload from a non-cleavable ADC in human serum.

Bioanalysis·2026

A validated bioanalytical LC-MS/MS method for the simultaneous determination of molnupiravir, N-hydroxycytidine, and baricitinib in human plasma.

Bioanalysis·2026

Electrochemiluminescence immunoassay for quantifying ZMA001 in human serum: method development, validation, and clinical pharmacokinetic application.

Bioanalysis·2026

Cell-specific cPGES control of glucocorticoid receptor function drives MASLD progression.

Cell reports·2026

1-Aminocyclopropane-1-Carboxylate and Its Chemoreceptor Drive Metabolic Reprogramming to Enhance Chemotactic Rhizocompetence in Pseudomonas sp. UW4.

Microorganisms·2026

From Solvent Design to Biological Response: Structure-Property Relationships of Edible Natural Deep Eutectic Solvents for the Extraction of Nigella sativa Bioactives.

Molecules (Basel, Switzerland)·2026

Molecular Characterization and RNAi-Based Functional Validation of Ache in the Neonicotinoid Stress Response of the Melon Fly, Zeugodacus cucurbitae.

Insects·2026

Enhancing materials discovery with valence-constrained design in generative modeling.

Nature computational science·2026

Autonomous bioisosteric replacement for multi-property optimization in drug design.

Nature communications·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us