Differential Functional Connectivity Between Silent Reading and Resting-State fMRI and Their Relationships With...

The clinical diagnostic parameters of dyslexia and the alterations it creates on brain connectivity continue to be the focus of current studies. In this study, where clinical neuropsychiatric tests and neuroimaging results are examined together, it is aimed to examine the functional connectivity differences that occur in the brain regions related to the reading pathway in children with dyslexia in a resting state and task-based manner and to compare them with healthy controls. Correlation analyses were performed to evaluate the correlation between the resting state and the reading task of the groups with age, word reading count and WISC-4 score and mean brain activity. The findings indicate that dyslexia is linked to deficits in the phonological component and that the correlation between intelligence and reading speed is lower in the dyslexia group than in healthy controls. It has also been observed that children with dyslexia have difficulties in the development of phonological input, semantics and phonological output, independent of intelligence and that neuronal connections are affected in a similar way. These findings contribute to the functional differences detected in dyslexia by neuroimaging, and may help to understand the complex nature of dyslexia and to make educational and therapeutic methods more effective.