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The Application of Foundation Models in Radiology: Bridging Images, Reports, and Beyond
Journal of the Korean Society of Radiology
|December 19, 2025
Summary
Foundation models are advancing artificial intelligence (AI) in radiology by learning from vast imaging and clinical data. This review explores their technical aspects, applications in image-only, chest X-ray, and other modalities, and future directions for personalized radiology.
Area of Science:
- Radiology
- Artificial Intelligence
- Medical Imaging
Background:
- Artificial intelligence (AI) in radiology is evolving towards foundation models.
- These models learn universal representations from large-scale imaging and multimodal clinical data.
Purpose of the Study:
- To review the technical components of foundation models in radiology.
- To summarize recent advancements in image-only, chest X-ray image-report, and other image-report models.
- To discuss evaluation strategies, clinical validation, and future directions.
Main Methods:
- Review of technical components: self-supervised encoders, fusion modules, task-specific decoders.
- Categorization of recent work: image-only, chest X-ray image-report, and other image-report models.
- Discussion of evaluation strategies: vision-centric, language-centric, benchmark-based metrics, and clinical validation.
Main Results:
- Foundation models enable robust transfer learning with minimal annotation through self-supervised learning on unlabeled radiology scans.
- Joint visual and textual embeddings are achieved using large chest X-ray-reported corpora.
- Multimodal fusion integrates volumetric images with structured reports or clinical metadata for diverse applications.
Conclusions:
- Foundation models represent a significant advancement in AI for radiology.
- Future directions include multimodal integration and human-AI collaboration for personalized radiology.
- Addressing persistent challenges is crucial for clinical application and validation.
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