Effectiveness of Transcatheter Arterial Embolization in Locally Advanced Triple-Negative Breast Cancer Resistant to...

A 74-year-old woman was diagnosed with locally advanced invasive ductal carcinoma of the right breast, which was confirmed as triple-negative breast cancer (TNBC) by immunohisto-chemical analysis. Multiple ipsilateral axillary lymph node metastases were identified, but no distant metastases were detected. The patient underwent neoadjuvant chemotherapy, which was ineffective, and subsequently developed tumor-related wound bleeding. To control the bleeding and reduce tumor vascularity, transcatheter arterial embolization (TAE) was performed. Permanent embolization using Embosphere microspheres and glue induced in complete ischemia, leading to a significant reduction in tumor and lymph node size, thereby enabling surgical resection. A follow-up examination one year later revealed no evidence of recurrence or metastasis. This case report highlights the potential therapeutic efficacy of TAE in the management of locally advanced TNBC resistant to neoadjuvant chemotherapy.