Draft genome sequences of two clinical isolates of Candida tropicalis from Iraq

Wafaa S H Al-Nasrawi1,2, Ban T Mohammed1, Adnan A Lahuf3

  • 1Department of Biology, College of Education for Pure Science, University of Kerbala, Karbala, Iraq.

PubMed

Insights

Two multidrug-resistant Candida tropicalis isolates from Iraq hospitals were sequenced. This research provides genomic data on this emerging pathogen linked to oral candidiasis and hospital outbreaks.

Area of Science:

  • Medical Mycology
  • Genomics
  • Infectious Diseases

Background:

  • Candida tropicalis is an emerging fungal pathogen.
  • It is frequently associated with oral candidiasis.
  • Multidrug resistance in Candida species is a growing public health concern.

Purpose of the Study:

  • To report the draft genome sequences of two multidrug-resistant Candida tropicalis isolates.
  • To provide genomic resources for understanding Candida tropicalis outbreaks and resistance.

Main Methods:

  • Whole-genome sequencing of two clinical isolates of Candida tropicalis.
  • Bioinformatic analysis of the obtained draft genome sequences.

Main Results:

  • The study reports the draft genome sequences of two multidrug-resistant Candida tropicalis isolates.
  • These isolates were associated with hospital outbreaks in Karbala province, Iraq.

Conclusions:

  • The genomic data will aid in studying the evolution and epidemiology of multidrug-resistant Candida tropicalis.
  • Understanding the genetic basis of resistance is crucial for developing effective treatments against Candida tropicalis infections.