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Cardiovascular Disease Classification System With ECG-Gating PCG Algorithm and Programmable AI Accelerator Design
Insights
This study introduces a wearable system for real-time cardiovascular diagnosis, improving accuracy for arrhythmia and heart valve diseases. The novel hardware and algorithms enable efficient, on-device detection of critical cardiac conditions.
Area of Science:
- Biomedical Engineering
- Cardiology
- Computer Engineering
Background:
- Cardiovascular diseases (CVDs) are a leading cause of mortality, necessitating improved diagnostic tools.
- Current methods for diagnosing cardiac conditions often require clinical settings, limiting timely detection.
- Wearable devices with edge-computing offer potential for real-time, accessible cardiovascular health monitoring.
Purpose of the Study:
- To develop a wearable system for accurate, real-time diagnosis of cardiovascular diseases, specifically arrhythmia and heart valve diseases (HVDs).
- To address the challenges of implementing complex classification models on resource-constrained wearable devices.
- To create an efficient hardware accelerator for multiple diagnostic models.
Main Methods:
- An ECG-gating algorithm was developed to improve phonocardiogram (PCG) signal analysis.
- Advanced classification algorithms were implemented for arrhythmia and HVD detection.
- A systolic array-based accelerator with an application-specific instruction-set processor (ASIP) was designed and fabricated.
Main Results:
- The algorithms achieved high accuracy: 97.8% for arrhythmia and 99.3% for HVD, with minimal hardware quantization error (<0.5%).
- The fabricated accelerator demonstrated low power consumption (414 μW at 1 MHz) and fast classification times (7.2 ms for arrhythmia, 21 ms for HVD).
- Exceptional energy efficiency was achieved (395.3 GOPS/W normalized to 40 nm).
Conclusions:
- The developed system effectively classifies arrhythmia and heart valve diseases using wearable technology.
- The combination of advanced algorithms and a specialized hardware accelerator enables efficient on-device cardiac diagnosis.
- This technology holds significant promise for improving early detection and management of cardiovascular conditions.
Abstract:
Cardiovascular diseases (CVDs) are among the leading causes of mortality. Traditional diagnostic methods require hospital visits and professional medical personnel, but the timely detection of cardiac conditions can significantly improve survival rates. Therefore, wearable devices with edge-computing capabilities for real-time cardiovascular diagnosis are highly important. Heart sounds provide valuable information on valve closure; however, variations in heart rhythm or heart valve diseases (HVDs) can complicate the identification of affected valves and the interpretation of heart sound origins. Additionally, different disease classifications require distinct model architectures, posing significant challenges for implementation on wearable devices. This study addresses these challenges through three key contributions: an ECG-gating PCG algorithm, improved classification algorithms for arrhythmia and valvular heart disease, and a systolic array-based accelerator with an application-specific instruction-set processor (ASIP) capable of performing inference on multiple models. The algorithms achieve 97.8% and 99.3% accuracy on the MIT-BIH and heart murmur databases, respectively, with hardware quantization errors below 0.5%. The accelerator is fabricated in TSMC 180 nm CMOS technology, achieving an operating power of 414 µW at 1 MHz. The execution times for arrhythmia and valvular heart disease classification are 7.2 ms and 21 ms, respectively, and the energy efficiency normalized to 40 nm is 395.3 GOPS/W. These show that this system can effectively solve the classification of arrhythmia and heart valve diseases.
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