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The Effect of Smartphone Pre-Notification System on Regional Acute Ischemic Stroke Management Time Delay: Multicenter
Haewon Jung1, Hyun Wook Ryoo1, Jae Yun Ahn1
1Department of Emergency Medicine, School of Medicine, Kyungpook National University, Daegu, Korea.
Prehospital Emergency Care
|December 19, 2025
Summary
Smartphone prenotification systems like FASTroke significantly reduce treatment times for acute ischemic stroke (AIS) patients. This mobile application improved door-to-CT scan, door-to-thrombolysis, and door-to-thrombectomy times, especially with preregistration.
Area of Science:
- Neurology
- Emergency Medicine
- Health Informatics
Background:
- Prehospital notification is vital for reducing door-to-reperfusion time in acute ischemic stroke (AIS) patients.
- Real-world effectiveness of smartphone prenotification systems for AIS needs further investigation.
- A mobile application-based prenotification system (FASTroke) was implemented in Daegu, South Korea, to optimize acute stroke care.
Purpose of the Study:
- To analyze the impact of the FASTroke prehospital notification system on reducing treatment time delays in acute ischemic stroke (AIS) patients.
- To evaluate the effectiveness of smartphone application utilization in streamlining acute stroke care pathways.
- To assess the influence of the pre-notification system on key time metrics in AIS management.
Main Methods:
- A retrospective observational before-and-after study design was employed in Daegu, South Korea.
- Patients with AIS arriving via emergency medical services were categorized based on FASTroke system usage (before and after implementation).
- Key time variables including Door-to-CT scan time (DTC), Door-to-intravenous thrombolysis time (DTI), and Door-to-endovascular thrombectomy time (DTE) were analyzed using multivariable logistic regression.
Main Results:
- The FASTroke system significantly reduced DTC (23.0 to 20.0 min), DTI (42.5 to 36.0 min), and DTE (95.5 to 87.0 min) compared to the pre-implementation period.
- The preregistration feature within FASTroke further enhanced time reductions: DTC by 14.0 min, DTI by 33.0 min, and DTE by 66.5 min.
- FASTroke use significantly increased the odds of achieving DTC < 20 min (aOR 1.971) and DTE < 90 min (aOR 2.010), with greater odds in the preregistration subgroup.
Conclusions:
- The FASTroke mobile application significantly improved in-hospital treatment timelines for acute ischemic stroke patients.
- The preregistration feature of the FASTroke system demonstrated a substantial positive impact on reducing critical treatment times.
- Smartphone-based prehospital notification systems are effective tools for optimizing acute stroke care delivery.
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