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Updated: Jan 8, 2026
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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
Published on: December 11, 2016
10.1K
Geopolitical contributions to pharmaceutical innovation
Michael S Kinch1, Aayan Alawi1, Tyler Schwartz2
1Department of Pharmaceutical Sciences, Stony Brook University, Stony Brook, NY, USA.
Drug Discovery Today
|December 19, 2025
Summary
New experimental drug discovery has surged globally over 25 years. China
Area of Science:
- Pharmaceutical Sciences
- Drug Discovery and Development
- Global Health Initiatives
Background:
- The United States private sector has historically led global new drug introductions.
- The landscape of pharmaceutical innovation is dynamic and evolving.
- Understanding the origins of new experimental drugs is crucial for future R&D strategies.
Purpose of the Study:
- To analyze the geographical sources of new experimental drugs in the 21st century.
- To identify shifts in drug discovery leadership.
- To assess the impact of national strategies on pharmaceutical innovation.
Main Methods:
- Analysis of drug discovery organizational origins.
- Tracking the number and sources of new experimental drugs over time.
- Comparative assessment of contributions from different countries and sectors.
Main Results:
- A significant increase in the overall number of new experimental drugs over the past 25 years.
- China has emerged as a major player, now matching US contributions in new drug discovery.
- This growth in China reflects coordinated public and private sector efforts.
Conclusions:
- The rise of China signifies a major shift in global pharmaceutical R&D leadership.
- Future pharmaceutical enterprise decision-making and leadership will be influenced by these changes.
- International collaboration and competition dynamics in drug discovery are transforming.
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