[Human resources framework to obtain JACIE accreditation (SFGM-TC)]

International organizations FACT and the Joint Accreditation Committee ISCT-Europe & EBMT (JACIE) have developed a reference framework that provides a safe structure for the management of cellular therapies. This framework (FACT-JACIE v8.2) is organized according to a quality management approach. During the annual workshops of the Société francophone de greffe de moelle et de thérapie cellulaire (SFGM-TC), we aimed to enable medical directors to build an effective human resource management system that complies with JACIE standards. To this end, we designed a competency validation system, including an annual cycle for physicians and a three-year cycle for paramedical staff, structured around three key domains. By clearly distinguishing the training pathway and integrating digital tools, this model ensures real-time updating of competencies and can be extended to other specialties or healthcare professions, as well as reproduced at the national level with international perspectives. This article lays the foundations of a collaboratively developed skills enhancement program. It describes the necessary steps to fully involve each professional category in its design, details the mechanisms that foster their engagement, and identifies the essential elements to define and implement in order to achieve an operational competency matrix. The entire approach is carried out in compliance with FACT-JACIE requirements, ensuring its robustness and international alignment.