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Safety Outcomes of Hybrid Open Chest Transvenous Lead Extraction: A Multicenter Experience
Nadeev Wijesuriya1,2, Helena Lytton Cobbold2, Keisha Kellman2
1King's College London, London, UK.
Pacing and Clinical Electrophysiology : PACE
|December 22, 2025
Summary
Hybrid open chest transvenous lead extraction (TLE) shows high success rates for complex cases. Chronic lung disease is a key predictor of complications, guiding patient selection for this advanced procedure.
Area of Science:
- Cardiovascular Surgery
- Electrophysiology
- Medical Device Extraction
Background:
- Hybrid open chest transvenous lead extraction (TLE) combines surgical and endovascular methods for complex cases.
- Data on outcomes for TLE in patients needing cardiac surgery or with high-risk features is limited.
Purpose of the Study:
- To assess procedural outcomes of elective hybrid open chest TLE.
- To identify predictors of complications in patients undergoing this procedure.
Main Methods:
- Retrospective multicenter cohort study of 40 patients (2017-2025).
- Exclusion of emergency surgical conversions.
- Analysis of baseline, procedural, and outcome data, including in-hospital mortality and complications (modified Delphi classification).
- Logistic regression used to identify complication predictors.
Main Results:
- High clinical procedural success (97.5%) with low in-hospital mortality (2.5%).
- Severe complication rate was 15%, overall complication rate was 37.5%.
- Chronic lung disease predicted severe complications (OR 102.2, p=0.03); atrial fibrillation predicted any complication (OR 5.83, p=0.04).
Conclusions:
- Hybrid open chest TLE offers high success with acceptable mortality despite significant morbidity.
- Chronic lung disease is an independent predictor of complications, crucial for patient selection and planning.
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