Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Ligand-Driven Aldehyde Condensation via Zeolitic Imidazolate Framework-Based Pro-Nanozymes with Formolase-like Activity.

ACS nano·2026

Same author

Mineral-Derived Nanozymes Modulate Plant Redox Homeostasis and Nitrogen Metabolism to Improve Crop Productivity.

ACS nano·2026

Same author

A RIG-I targeting nanozyme induces PANoptosis for cancer immunotherapy.

Nature communications·2026

Same author

Multi-Activity Nanozyme-Integrated Scaffolds: Harnessing Synergistic Enzyme-like Effects for Complete Treatment of Infected Bone Defects.

ACS nano·2026

Same author

Beyond Catalytic Therapy: Copper-Paeonol Nanozymes Disrupt Fascin-Mediated Actin Bundling to Suppress Tumor Growth and Metastasis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025

Same author

Nanozymes modulate probiotic tryptophan metabolism to prevent Salmonella infection in mammalian models.

Nature microbiology·2025

Same journal

Reconfigurable Multistate Optical Memory in Mixed Halide Perovskites.

ACS applied materials & interfaces·2026

Same journal

Tunable, High-Relaxivity Gd(III)-Conjugated Lipoic Acid Hydrogels for Magnetic Resonance Imaging.

ACS applied materials & interfaces·2026

Same journal

Effects of Metal Ions of Metal-Organic Framework Membranes on the Transport of NaCl Solutions toward Seawater Desalination.

ACS applied materials & interfaces·2026

Same journal

Immobilization of Single Ni Sites and Separated Pd Clusters in Covalent Organic Framework for Enhanced Electrochemical Reduction of Nitrite to Ammonia.

ACS applied materials & interfaces·2026

Same journal

Evidence for Step-Edge-Assisted Large Hole Borophene on Ni(111).

ACS applied materials & interfaces·2026

Same journal

Growth Mode-Dependent Bi Incorporation and Carrier Localization in GaAsBi Wires.

ACS applied materials & interfaces·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 8, 2026

Bioluminescent Bacterial Imaging In Vivo

Bioluminescent Bacterial Imaging In Vivo

Published on: November 4, 2012

Targeting Intratumoral Bacteria for Cancer Nanotherapeutics.

Ying Wang¹, Jian Yu¹, Lizeng Gao^2,3

¹Beijing Advanced Innovation Center for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Engineering Medicine, Beihang University, Beijing 100191, China.

ACS Applied Materials & Interfaces

|December 22, 2025

Summary

This summary is machine-generated.

Nanotechnology offers precise control over intratumoral microbiota, enhancing cancer treatment by targeting bacteria. This approach overcomes limitations of antibiotics for improved therapeutic outcomes.

Keywords:

intratumoral bacteria nanotechnology therapeutic strategies tumor

More Related Videos

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

Inducing Targeted Mild Hyperthermia in Murine Tumor Models through Photothermal Conversion of Near-infrared Light by Intratumoral Gold Nanorods

Inducing Targeted Mild Hyperthermia in Murine Tumor Models through Photothermal Conversion of Near-infrared Light by Intratumoral Gold Nanorods

Published on: October 10, 2025

Related Experiment Videos

Last Updated: Jan 8, 2026

Bioluminescent Bacterial Imaging In Vivo

Bioluminescent Bacterial Imaging In Vivo

Published on: November 4, 2012

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

Inducing Targeted Mild Hyperthermia in Murine Tumor Models through Photothermal Conversion of Near-infrared Light by Intratumoral Gold Nanorods

Inducing Targeted Mild Hyperthermia in Murine Tumor Models through Photothermal Conversion of Near-infrared Light by Intratumoral Gold Nanorods

Published on: October 10, 2025

Area of Science:

Oncology
Microbiology
Nanotechnology

Background:

Intratumoral microbiota significantly impacts cancer progression and treatment response.
Conventional methods like antibiotics for microbiome modulation yield inconsistent results and harm beneficial microbes.

Purpose of the Study:

To review nanotechnology's role in selectively regulating intratumoral microbiota.
To classify nanotechnology's antibacterial mechanisms against intratumoral bacteria.
To discuss nanomaterial design, therapeutic outcomes, and future clinical applications.

Main Methods:

Comprehensive literature analysis of nanotechnology-based strategies for intratumoral microbiota.
Classification of antibacterial mechanisms into physical, chemical, and biological modalities.
Examination of precision design, therapeutic effects, and safety challenges.

Main Results:

Nanotechnology provides precise control over intratumoral bacteria via physical, chemical, or biological mechanisms.
Tailored nanomaterial design enhances targeted antimicrobial activity within the tumor microenvironment.
This approach shows promise for overcoming antibiotic resistance and improving cancer therapy.

Conclusions:

Nanotechnology presents a powerful tool for modulating the tumor microbiome and enhancing cancer treatment efficacy.
Further research into precise targeting, safety, and translational progress is crucial for clinical application.
Developing advanced nanotechnology-based strategies can lead to more effective and personalized cancer therapies.