Related Experiment Video
Updated: Jan 7, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
The breakthrough discoveries for thriving with bipolar disorder (BD2) integrated network longitudinal cohort protocol
Emily G Baxi1, Megan Shanahan2, Daniel L Pham1
1Breakthrough Discoveries for Thriving With Bipolar Disorder, Milken Institute Science Philanthropy Accelerator for Research and Collaboration, Washington, DC, USA.
None:
Bipolar Disorder (BD) is a highly complex and heterogeneous disorder. As such, accurate diagnosis is often delayed, and effective treatment options are limited. The Integrated Network, a program of Breakthrough Discoveries for thriving with Bipolar Disorder (BD2), was designed as a platform for longitudinal deep phenotyping of a diverse group of people with bipolar disorder to define disease trajectories and to gain insight into the biological drivers of the illness. Biosamples, including whole blood, serum, plasma, and peripheral blood mononuclear cells (PBMCs), will be collected longitudinally and will also be made available. The Integrated Network is designed to be the largest and most comprehensive prospective longitudinal study conducted in bipolar disorder, allowing for the development of precision-based treatment strategies that optimize quality of life for people living with bipolar disorder.
More Related Videos
05:19Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment
Published on: July 7, 2023
08:33Olfactory Neurons Obtained through Nasal Biopsy Combined with Laser-Capture Microdissection: A Potential Approach to Study Treatment Response in Mental Disorders
Published on: December 4, 2014
Related Concept Videos
Bipolar Disorder
Long-term Depression
Calcium Ion Concentration Mechanism
If over...
Long-term Depression
Borderline Personality Disorder
Genetic and Environmental Contributions
Borderline Personality...
Longitudinal Studies
Treatment Strategies for Psychological Disorders
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...