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Implementation of a Mobile Digital Tool Supporting Medication for Opioid Use Disorder Treatment Improves Retention:
Jorge E Palacios1, Robert Sherrick2, Tim Janssen3
1Bright Therapeutics, San Francisco, CA, United States.
Journal of Medical Internet Research
|December 22, 2025
Summary
Digital tools like Recovery Connect significantly improve retention for medication for opioid use disorder (MOUD) treatment. Early app engagement is key to better treatment continuity and adherence for patients in recovery.
Area of Science:
- Digital Health
- Substance Use Disorder Treatment
- Health Services Research
Background:
- Medication for opioid use disorder (MOUD) retention is low due to systemic and individual barriers.
- Digital interventions show promise but lack robust evidence for improving MOUD treatment retention.
- Recovery Connect is a digital remote patient monitoring app integrated into a blended MOUD treatment model.
Purpose of the Study:
- To evaluate the impact of Recovery Connect on patient retention in MOUD treatment.
- To assess the effect of the app on treatment continuance and medication adherence.
- To determine the role of app linkage and engagement in MOUD treatment outcomes.
Main Methods:
- A stepped-wedge cluster randomized trial was conducted across 9 outpatient MOUD clinics.
- Clinics were transitioned from usual care to a digitally enhanced model using Recovery Connect.
- Primary outcome was 30-day retention; secondary outcomes included treatment continuance and medication adherence.
Main Results:
- Clinics implementing Recovery Connect showed significantly higher 30-day retention rates (75.5% vs. 63.6%).
- Patients linked with the app demonstrated higher retention (81.3% vs. 72.0%), continuance, and adherence.
- Progressively higher app engagement levels were associated with significantly better 30-day retention.
Conclusions:
- Recovery Connect implementation significantly enhances patient retention and treatment continuity in MOUD care.
- Early app linkage and engagement strongly predict positive treatment outcomes.
- Blended digital-clinical models, including remote monitoring, improve care continuity and support recovery.
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