Related Experiment Video For Cancer
Updated: Jan 8, 2026
Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells
Published on: December 9, 2016
Risk factors for cancer among the working population in China: a cross-sectional analysis of baseline data from the
Kaige Sun1, Baohua Wang2, Feng J He3
1Beijing Physical Examination Center, Beijing, China.
Objective:
This study aims to assess the prevalence of cancer risk factors in China's working population and provide evidence for formulating more targeted workplace cancer prevention strategies.
Design:
A cross-sectional study utilising the baseline data from the Comprehensive Workplace Intervention for Cancer Prevention in China (WECAN) project, a stepped-wedge cluster randomised controlled trial.
Setting:
15 workplaces from three cities in China: Wuhai (Northern China), Nanchong (Western China) and Xiangtan (Southern China).
Participants:
A total of 841 participants (56 employees per workplace) were recruited through stratified sampling based on sex and work type.
Primary Outcome Measures:
The prevalence of self-reported cancer risk factors, including smoking, alcohol consumption, physical inactivity, obesity, unhealthy diet, betel quid chewing, exposure to harmful gases or substances, biological screening and vaccination.
Results:
The study included 841 participants (mean age 40.5±8.9 years; 61.4% male, 57.4% blue-collar workers, 47.3% aged <40 years), with 36.4% reporting family cancer history. The reported cancer risks included smoking (36.9%, male-female OR=40.4 (95% CI 21.6 to 75.7)), alcohol consumption (63.6%, male-female OR=4.3 (95% CI 3.0 to 6.0)), physical inactivity (49.1%), central obesity (36.7%, male-female OR=3.2 (95% CI 2.3 to 4.5)), unhealthy diet (95.8% with two or more of six unhealthy dietary habits), betel quid chewing (18.8%, male-female OR=3.3 (95% CI 1.9 to 5.9), with 97.5% in Xiangtan), preference for hot foods (5.0%, older-younger OR=2.5 (95% CI 1.1 to 5.6)), household air pollution (7.0%, higher risk among lower-educated individuals), unprotected occupational exposure (6.1%, male-female OR=2.8 (95% CI 1.3 to 6.0), blue-white collar OR=2.1 (95% CI 1.0 to 4.5)), no screening for hepatitis B surface antigen (46.4%) and helicobacter pylori (54.9%), and unvaccinated against hepatitis B virus (28.1%) and human papillomavirus (63.5% among females≤45 years). Regional heterogeneity was observed for nearly all risk factors.
Conclusions:
The working population faces significant cancer risk factors, with variations across populations and regions highlighting the need for targeted interventions.
Trial Registration Number:
ChiCTR2200058680.
Related Concept Videos
02:59Cancer Prevention
Some...
02:17The Tumor Microenvironment
02:12What is Cancer?
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
01:12Loss of Tumor Suppressor Gene Functions
When the tumor suppressor genes develop mutations or are lost, cells start growing out of control, leading to cancer. However, a single functional copy of the tumor suppressor gene is enough for the cells to maintain their normal functions and cell...
02:18Cancer
01:25Statistical Methods for Analyzing Epidemiological Data