Association between vitamins intake and kidney stone: A cross-sectional study

Area of Science:

• Nutrition Science
• Urology
• Public Health

Background:

• Kidney stones (KS) are a significant health concern.
• Dietary factors, including vitamin intake, may influence KS development.
• Understanding these relationships is crucial for prevention strategies.

Purpose of the Study:

• To investigate the association between dietary vitamin A, C, D, and E intake and the prevalence of kidney stones in US adults.
• To identify potential protective or risk-increasing vitamin-related dietary patterns for kidney stone formation.

Main Methods:

• Utilized data from 5721 participants in the National Health and Nutrition Examination Survey (NHANES).
• Employed logistic regression models to analyze associations between vitamin intake tertiles and KS prevalence.
• Subgroup analyses were conducted to confirm findings across different demographics.

Main Results:

• Vitamin C and E intake showed a negative association with kidney stone prevalence (P trend < .01).
• Higher intake of vitamin C and E was linked to lower odds of developing kidney stones.
• Vitamin D intake demonstrated a positive association with kidney stone prevalence (P trend < .01).
• Increased vitamin D consumption correlated with higher odds of kidney stones.

Conclusions:

• Dietary vitamin C and E intake may play a protective role against kidney stone development.
• Elevated vitamin D intake appears to be associated with an increased risk of kidney stones.
• These findings suggest specific vitamin modulations in diet could impact kidney stone prevalence.