Anterior segment optical coherence tomography imaging in angle closure: advances in diagnosis and care

To highlight emerging applications of anterior segment optical coherence tomography (AS-OCT) in the diagnosis, risk stratification, and management of angle closure glaucoma, with particular emphasis on the integration of artificial intelligence.

AS-OCT enables objective and reproducible quantification of anterior chamber angle parameters, overcoming the subjective and qualitative nature of traditional gonioscopy. Recent studies also suggest that AS-OCT can better predict angle closure disease and treatment outcomes than gonioscopy. Furthermore, advances in artificial intelligence-based image analysis have achieved expert-level accuracy in detecting angle closure and related anatomical features, facilitating personalized risk stratification and treatment planning. Overall, these advancements show strong potential for broad adoption to enhance clinical care and workflows.

High-resolution AS-OCT imaging combined with artificial intelligence-driven analytics is transforming the evaluation and management of angle closure disease. This noninvasive, objective approach has the potential to augment traditional methods, paving the way for more precise, personalized, and evidence-based care. Broad clinical adoption requires further rigorous prospective validation across large and diverse patient populations.