New Ligands Beyond N-Heterocyclic Carbenes for Application in Homogeneous Catalysis
Kevin Salzmann1, Esaie Reusser2, Nicolas Lentz3
1Department of Chemistry, Biochemistry, and Pharmaceutical Sciences, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland. kevin.salzmann@lonza.com.
Abstract:
Building on the success of N-heterocyclic carbenes, extended versions comprised of an exocyclic metal bonding site have become increasingly popular. Pyridinium amidates (PYAs) belong to these ligand systems, as they contain a N-donor site that is formally stabilized by a pyridine-derived carbene. These PYAs are characterized by a unique donor flexibility, which imparts in some settings extraordinarily high catalytic activity, and in other settings remarkable stability of (catalytic) intermediates, which allows for deciphering mechanistic pathways.
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