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Updated: Jan 8, 2026

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
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Public Health.

Phenphichcha Chuchuen1,2, Phot Dhammapeera1, Chavit Tunvirachaisakul2,3,4

  • 1Faculty of Psychology, Chulalongkorn University, Bangkok, Thailand.

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|December 23, 2025
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Summary

This study found that an 8-session Multi-modal Cognitive Stimulation Program (MCSP) significantly improved cognition and quality of life in older Thai adults with mild cognitive impairment (MCI). The intervention group showed better cognitive scores and QOL compared to the control group.

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Area of Science:

  • Gerontology
  • Neuroscience
  • Public Health

Background:

  • Mild cognitive impairment (MCI) is a significant global health concern, particularly for aging populations.
  • Thailand faces a growing challenge with MCI, increasing the risk of dementia in older adults.
  • Multi-modal Cognitive Stimulation Programs (MCSP) offer a non-pharmacological approach to mitigate cognitive decline.

Purpose of the Study:

  • To evaluate the efficacy of an 8-session MCSP on cognitive function and quality of life (QOL) in Thai older adults diagnosed with MCI.
  • To compare the outcomes of MCSP intervention against a control group in a randomized controlled trial setting.

Main Methods:

  • A randomized controlled trial involving 66 Thai older adults with MCI, divided into intervention (n=32) and control (n=34) groups.
  • Cognitive assessments included MMSE, CERAD, Color Trail Test, and Digit Span; QOL was measured using QOL-AD.
  • Data analysis employed chi-square and t-tests for demographics, and Generalized Estimating Equations (GEE) for cognitive and QOL outcomes.

Main Results:

  • The intervention and control groups exhibited no significant baseline differences in demographics, cognitive scores, or QOL.
  • Following the 8-session MCSP, the intervention group demonstrated statistically significant improvements in cognitive scores and QOL compared to the control group.
  • GEE analysis indicated that group, age, education, and initial scores significantly predicted cognitive score changes, while group, initial scores, and group by time interaction significantly affected QOL scores.

Conclusions:

  • An 8-session MCSP intervention significantly enhanced both cognitive function and quality of life in Thai older adults with MCI.
  • The findings support MCSP as an effective non-pharmacological strategy for managing MCI in older populations.
  • The study highlights the positive impact of targeted cognitive interventions on improving health outcomes for individuals with MCI.