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Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
Published on: August 22, 2012
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Public Health
Meng Wei1, Qiumin Qu2, Suhang Shang2
1First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 23, 2025
Summary
This study found no direct link between coronary heart disease (CHD) and cognitive impairment in rural adults. However, the combination of CHD and diabetes significantly elevates the risk of cognitive impairment.
Area of Science:
- Gerontology
- Cardiology
- Neurology
Background:
- Cardiovascular disease (CVD) and cognitive impairment are major public health concerns.
- Shared risk factors like hypertension and obesity link CVD and cognitive decline.
- Previous research on CVD and cognitive impairment primarily involved hospitalized patients.
Purpose of the Study:
- To investigate the correlation between coronary heart disease (CHD) and cognitive impairment.
- Focus on rural populations aged 40 and above.
- Examine the impact of comorbidities on cognitive function in CHD patients.
Main Methods:
- Cross-sectional study of 1,833 rural residents aged 40+.
- Cognitive function assessed using the Mini-Mental State Examination (MMSE).
- Multivariate logistic regression adjusted for confounding factors.
Main Results:
- Unadjusted analysis showed higher cognitive impairment in CHD patients (24.6% vs 12.9%).
- Adjusted analysis revealed no statistically significant association between CHD and cognitive impairment (OR=1.265).
- CHD combined with diabetes significantly increased cognitive impairment risk (OR=4.712).
Conclusions:
- No direct association was found between coronary heart disease and cognitive impairment.
- The combination of CHD and diabetes significantly increases the risk of cognitive impairment.
- Further prospective studies with larger sample sizes are recommended.
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