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Updated: Aug 3, 2026

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
Published on: February 9, 2021
Four new glycoside compounds from Sinapis alba L. and their cytotoxic activity
Degang Kong1, Xinyu Shi1, Linlin Ni2
1College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, P. R. China.
Abstract:
Four novel compounds, 4-hydroxybenzyl-7-S-β-glucopyranoside (1), 4-hydroxybenzyl-7-S-S-β-glucopyranoside (2), 1-S-(4'-hydroxybenzyl)-6-(4''-hydroxybenzoyl)-β-glucopyranoside (3), and 1-O-(4'-hydroxybenzoyl)-2-O-Z-sinapoyl-β-glucopyranoside (4) were used to isolate from Sinapis alba L. seeds. The structures were accomplished through spectroscopic analysis (NMR and MS) corroborated by chemical studies. Three human cancer cell lines were employed to detect the cytotoxic effects of the compounds.
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