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Growth and development in children receiving hemodialysis
Southern Medical Journal
|February 1, 1978
Insights
Children with end-stage renal disease on prolonged intermittent hemodialysis showed significant growth and development. Good nutrition alongside dialysis may optimize growth before kidney transplantation.
Area of Science:
- Pediatric Nephrology
- Renal Replacement Therapy
Background:
- End-stage renal disease (ESRD) in children poses significant challenges to growth and development.
- Optimizing growth in pediatric ESRD patients is crucial for long-term outcomes.
Purpose of the Study:
- To evaluate the impact of prolonged intermittent hemodialysis on linear growth and sexual development in children with ESRD.
- To assess the potential of hemodialysis and nutrition to support growth prior to renal transplantation.
Main Methods:
- Retrospective analysis of five pediatric patients (aged 12-18 years) undergoing intermittent hemodialysis.
- Study duration up to 60 months, monitoring linear growth and development of secondary sexual characteristics.
Main Results:
- All five children demonstrated progression in linear growth and overall development.
- Observed growth rates ranged from 60% to 260% of the expected increment.
- Four out of five children achieved secondary sexual characteristics during treatment.
Conclusions:
- Prolonged intermittent hemodialysis can support significant linear growth and development in pediatric ESRD patients.
- Combined approach of hemodialysis and adequate nutrition may be beneficial for maximizing growth potential before renal transplantation.
Abstract:
Five children, aged 12 to 18 years, received intermittent hemodialysis for as long as 60 months. Linear growth and development progressed in all children. Growth rate was 60% to 260% of the expected increment. Four of the children developed secondary sexual characteristics. Prolonged hemodialysis combined with good nutrition may promote maximal growth before renal homotransplantation in children with end-stage renal disease.