Gastric Squamous Cell Carcinoma as a Cause of Clinically Unstable Gastrointestinal Bleeding

Gastric squamous cell carcinoma (GSCC) is rare, accounting for less than 1% of gastric malignancies. Due to its rarity, specifics regarding the clinical presentation and risk factors for this malignancy remain uncertain. We describe a rare case of primary GSCC presenting with unstable gastrointestinal bleeding. A 64-year-old woman with a history of vertical band gastroplasty and orthotopic liver transplant for primary biliary cholangitis presented to an outside hospital with melena and hypovolemic shock. Upper endoscopic evaluation was completed revealing an ulcerated, oozing gastric mass within the fundus of the excluded stomach. Biopsies of the mass were consistent with GSCC.