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Updated: Jan 8, 2026

Robotic Myotomy and Partial Fundoplication for Achalasia
Published on: August 11, 2023
Rituximab-Induced Esophageal Ulcers and Strictures Presenting as Dysphagia
Muhammad Anas Abdulrazzak1, Muhammed Yaman Swied1, Obada Daaboul1
1Department of Internal Medicine, Southern Illinois University School of Medicine, Springfield, IL.
None:
Rituximab is a monoclonal antibody that targets CD20 on B lymphocytes and is approved for the treatment of multiple hematological and autoimmune disorders. Rituximab may cause gastrointestinal side effects such as colitis, diarrhea, and bowel obstruction or perforation. Infusion-related reactions, such as throat irritation, are, however, not linked to any specific esophageal disease. In this study, we report an extremely rare case of rituximab-induced esophageal ulceration and stricture causing progressive, debilitating dysphagia, highlighting the importance of early recognition and prompt management to prevent long-term morbidity.
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