Related Experiment Video
Updated: Jan 7, 2026

Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow
Published on: December 15, 2023
Cardiovascular Responses to a Full Resistance Training Session Performed with and Without Blood Flow Restriction
Anderson Geremias Macedo1,2,3,4, Gabriel de Souza Zanini1,5,6, Danilo Alexandre Massini1,2
1School of Sciences (FC), São Paulo State University (UNESP), Bauru 17033-360, SP, Brazil.
Abstract:
Resistance training (RT) can induce cardiovascular overload, especially at high intensities. Blood flow restriction (BFR) has emerged as a low-load alternative that is potentially effective and safe, although its hemodynamic and respiratory effects remain controversial.
Background/Objectives:
The aim of this study was to compare cardiovascular responses between a high-load RT session (RT_HL; 70% of one repetition maximum-1RM) and a low-load session combined with BFR (RT_LL+BFR; 30% 1RM).
Methods:
Nineteen trained men (24.3 ± 3.9 years; 177.7 ± 6.3 cm; 84.7 ± 13.0 kg) performed the RT_HL and RT_LL+BFR protocols, with eight exercises for each protocol. The following variables-heart rate (HR), percentage of maximum heart rate (%HRmax), systolic blood pressure (SBP), diastolic blood pressure (DBP), and rate pressure product (RPP)-were assessed during the protocols.
Results:
Both protocols significantly increased HR (pre: 74 ± 8 bpm; post: RT_HL = 142 ± 9 bpm; RT_LL+BFR = 133 ± 6 bpm; p < 0.01), %HRmax (RT_HL = 72 ± 5%; RT_LL+BFR = 69 ± 4%; p < 0.01), SBP (RT_HL = 144 ± 6 mmHg; RT_LL+BFR = 140 ± 6 mmHg; p < 0.05), and RPP (RT_HL = 20,469 ± 1620; RT_LL+BFR = 18,637 ± 1253; p < 0.01) compared to resting values. No variable exceeded safety thresholds for RPP (<30,000; %HRmax < 75%), and DPB showed a slight elevation in both conditions (p < 0.05), but without differences between protocols (p = 0.28).
Conclusions:
Exercise load intensity was an important determinant of hemodynamic responses, but BFR elicited comparable stimuli with low load, thereby emphasizing improved safety to traditional high-load-intensity training.
More Related Videos
12:37Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine
Published on: February 9, 2016
07:26Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
Related Concept Videos
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be...
Vascular Resistance
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
Exercise and Muscle Performance
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Exercise Stress Test
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Autoregulation of Blood Flow
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....