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Related Concept Videos

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

749
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
749
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

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Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
516

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Updated: Jan 7, 2026

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
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Biomarkers.

Yulu Yan1, Huan Ma1, Zihan Wang1

  • 1The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 24, 2025
PubMed
Summary
This summary is machine-generated.

Delayed-onset post-stroke cognitive impairment (PSCI) affects 11.68% of patients. Higher baseline NIH Stroke Scale (NHISS) scores and increased cerebrovascular disease risk factors are linked to delayed PSCI development.

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Area of Science:

  • Neurology
  • Neuroscience
  • Public Health

Background:

  • Post-stroke cognitive impairment (PSCI) can manifest early or be delayed.
  • While early PSCI is common, the incidence and risk factors for delayed PSCI remain less understood.

Purpose of the Study:

  • To determine the incidence of delayed-onset PSCI.
  • To identify risk factors associated with delayed-onset PSCI in patients with acute cerebral infarction.

Main Methods:

  • 197 patients with acute cerebral infarction and no early PSCI were followed for 24 weeks.
  • Cognition was assessed using the MoCA; delayed PSCI was diagnosed by set criteria.
  • Logistic regression and correlation analyses identified risk factors.

Main Results:

  • The incidence of delayed-onset PSCI was 11.68%.
  • Higher baseline NIH Stroke Scale (NHISS) scores and fewer regular exercise rates were observed in the delayed PSCI group.
  • Multivariate analysis revealed higher baseline NHISS scores (OR=1.525) and a greater number of cerebrovascular disease risk factors (OR=2.904) were significantly associated with delayed-onset PSCI.

Conclusions:

  • Delayed-onset PSCI occurs in 11.68% of patients post-acute cerebral infarction.
  • Elevated baseline NHISS scores and multiple cerebrovascular disease risk factors are significant predictors of delayed-onset PSCI.