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Leisure-Time Physical Activity and Mortality in Chronic Obstructive Pulmonary Disease: A Nationwide Cohort Study
Chun-Chieh Wang1, Yu-Yen Chen2, Yung-Feng Yen3
1Division of Chest Medicine, Department of Internal Medicine, Puli Branch of Taichung Veterans General Hospital, Nantou, Taiwan; Department of Medical Imaging and Radiological Sciences, Central Taiwan University of Science and Technology, Taichung, Taiwan.
Objective:
To investigate the impact of leisure-time physical activity (PA) on all-cause and cause-specific mortality risk in individuals with chronic obstructive pulmonary disease (COPD).
Design:
Retrospective cohort study.
Setting:
Baseline information on leisure-time PA of the patients with COPD was gathered from the National Health Interview Survey (conducted in 2001, 2005, 2009, and 2013). Comorbidities were identified from the National Health Insurance dataset (2000-2021).
Interventions:
Not applicable.
Main Outcome Measures:
Mortality was confirmed using the National Death Registration.
Results:
A total of 6584 adults aged >18 years with COPD were enrolled in this survey. Among them, 3360 (51.0%) were men, with a mean (SD) age of 57.3 (17.7) years. During the 20 years of follow-up, 1760 (26.7%) deaths were observed. Kaplan-Meier survival curves showed a significant survival rate among the 3 groups (log-rank P<.001). After controlling for potential confounders, subjects with leisure-time PA of 0
Conclusions:
This study demonstrated the benefits of leisure-time PA in individuals with COPD. Engaging in at least 800 MET-minutes of PA per week was associated with a significantly reduced risk of death from all causes, especially cardiovascular and cancer-related deaths.
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