Neonatal resuscitation practices and outcomes: establishing the DRIVE network registry

Area of Science:

• Neonatology
• Pediatric Critical Care
• Health Services Research

Background:

• Limited understanding of neonatal resuscitation practices in diverse US birth facilities.
• Need for a standardized system to track delivery room interventions.

Purpose of the Study:

• Establish a robust infrastructure to characterize real-world delivery room resuscitation.
• Provide data on the incidence, characteristics, and outcomes of neonatal resuscitation.

Main Methods:

• Created the Delivery Room Intervention and Evaluation (DRIVE) Network Registry.
• Included liveborn infants receiving continuous positive airway pressure (CPAP) or more intensive interventions.
• Collected standardized data on patient characteristics, interventions, and outcomes from 10 founding hospitals.

Main Results:

• 6241 newborns (15.7%) received resuscitation interventions out of 39,878 live births.
• Resuscitation rates were highest in preterm infants (≤28 weeks gestation) and decreased with advancing gestational age.
• Significant hospital-level variation in resuscitation rates (8-34%) was observed, particularly in infants born at 34-36 weeks gestation.

Conclusions:

• The DRIVE Network Registry is a novel multicenter initiative.
• Registry data reveal inter-hospital variability in delivery room resuscitation practices.
• Findings will guide future research and quality improvement efforts to optimize neonatal care.