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Clinical Manifestations.

Claire M Alexander1, Kylie R Kadey2, Rhiana Schafer3

  • 1Ann Arbor VA Healthcare System, Ann Arbor, MI, USA.

Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association
|December 24, 2025
PubMed
Summary
This summary is machine-generated.

SuperAgers (adults 80+ with exceptional memory) and controls showed similar emotional well-being. Black SuperAgers reported lower affective fear, suggesting potential impacts of social determinants on cognitive aging.

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Area of Science:

  • Gerontology
  • Neuroscience
  • Psychology

Background:

  • Emotional and social well-being are linked to cognitive function in older adults.
  • SuperAgers, defined as individuals 80+ with memory comparable to younger adults, may benefit from strong social connections.
  • Previous research suggests interpersonal relationships are key to the SuperAging phenotype.

Purpose of the Study:

  • To compare emotional well-being in SuperAgers versus cognitively average peers (Controls) using the NIH Toolbox-Emotion Battery (NIHTB-EB).
  • To investigate emotional well-being differences based on sex and racial identity within SuperAgers and Controls.

Main Methods:

  • Utilized cross-sectional cognitive, demographic, and NIHTB-EB data from the multisite SuperAging Research Initiative.
  • Compared NIHTB-EB T-scores between SuperAgers (n=65) and Controls (n=71).
  • Conducted independent samples t-tests to analyze differences by sex and self-reported racial identity.

Main Results:

  • SuperAgers and Controls did not significantly differ in overall emotional well-being.
  • Both groups showed trends toward lower negative emotions and higher life satisfaction than the general population.
  • Males reported higher instrumental support and lower affective fear than females; Black SuperAgers reported lower affective fear than Black Controls.

Conclusions:

  • Cognitively healthy adults aged 80+ exhibit positive emotional well-being.
  • Observed sex differences in social support perception align with some prior studies but contradict others.
  • Lower affective fear in Black SuperAgers warrants further investigation into social determinants of health and cognitive aging.