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Author Spotlight: Development and Characterization of a Mouse Model for Abdominal Aortic Aneurysm
Published on: August 2, 2024
[Progress in research of epidemiological characteristics of aortic aneurysm and risk factors]
1School of Public Health, Health Science Center, Ningbo University, Ningbo 315211, China.
Abstract:
Aortic aneurysm (AA), a degenerative vascular condition with subclinical nature, demonstrates relatively low incidence rate but substantial risk for rupture related mortality.Given its insidious onset, absence of pathognomonic early symptoms, coupled with high case-fatality rate and low screening rate, AA frequently has missed or delayed diagnoses. Currently, there is a lack of drugs that can effectively prevent or reverse the progression of AA. The investigation of AA epidemiology and risk factors can facilitate not only the identification of populations at high-risk and timely screening, but also improve outcome through targeted risk factor modification. This paper synthesizes current evidence on AA epidemiological patterns and associated risk determinants to provide a theoretical framework to improvve the early prevention strategies and transform clinical therapy from reactive treatment to active prevention.
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